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The fda approved chloroquine in october 1949.
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homewood ca,warhurst dc,peters w,baggaley vc 1972 lysosomes, ph and the anti-malarial action of chloroquine.
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over time, other derivatives of quinine were released by the fda chloroquine in 1952 and hydroxychloroquine in 1955.
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the excretion of chloroquine and the major metabolite, desethylchloroquine, in breast milk was investigated in eleven lactating mothers following a single dose of chloroquine 600 mg base .
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mtor inhibitors in fgfr3-mutant bladder cancers render cells more sensitive to chloroquine-induced lysosomal cell death.
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