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Extended adjuvant treatment of early breast cancer in postmenopausal women after completion of 5 years of adjuvant tamoxifen therapy.
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again the higher risk a woman has of having a recurrence, the more she will lose by not taking tamoxifen.
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tamoxifen, which can stimulate thickening and growth of the endometrial uterine lining, can also stimulate this tissue when it is found outside the uterus, and may increase symptoms associated with endometriosis such as pain before and during menstruation, pain during or after sexual intercourse, and heavy or irregular bleeding .
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the most common side effects with tamoxifen are hot flashes, nausea vomiting, vaginal discharge, menstrual irregularities, vaginal bleeding, increased bone or tumor pain, lightheadedness, dizziness, peripheral edema swelling in extremities , fatigue, headache, visual acuity changes, vaginal dryness, hair thinning loss, and anorexia loss of appetite .
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